This could be the biggest practical improvement to Vista/Win7 I have found! Ever since using Vista and now Win7, I have found a small but continuous annoyance that the focus never seems to be where you want it. For example, in an application, I go to File - Open, get an Explorer window pop up, and the scroll wheel doesn't do anything because the focus is not in the central pane. I have other applications that do similar things, and I always have to remember to click in the pane first before the scroll will work. A solution. Install XMouseControl. It has an option marked, "Make scroll wheel scroll window under cursor". It now just scrolls wherever the cursor is, and is so much nicer to use.