can't send email

[#1]

two different pop3 accounts, one using outlook and the other using windows mail.
I can receive email on both accounts, I've checked settings and they look okay. Anyone know if there's an issue at the moment?

[#2]

Can you post any error message or other details?

[#3]

Thanks, from windows mail
An unknown error has occurred. Subject 'Andrew', Account: 'mail.plus.net', Server: 'relay.plus.net', Protocol: SMTP, Server Response: '421 Cannot connect to SMTP server 107.8.159.212 (107.8.159.212:25), connect error 10060', Port: 25, Secure(SSL): No, Server Error: 421, Error Number: 0x800CCC67
no problem sending from other non PLusnet accounts

[#4]

Quote

no problem sending from other non PLusnet accounts

Does that mean you're not currently connected from a PlusNet connection ? If so you will need to use Authenticated SMTP to allow you to send via relay.plus.net OR send via the local mail server of the network to which you are connected

[#5]

No. I'm connected to a plusnet ADSL line.
The other accounts I'm speaking about are mail accounts which are hosted elsewhere. They've got nothing to do with plusnet and work fine.
adie:quote

[#6]

Ok, well I've just tried here and relay.plus.net is working fine.
Since both Windows mail and Outlook both fail it doesnt look like a configuration error,
Is it possible that your AV or Firewall is getting in the way ?  I'm afraid being a Linux man I'm not not much use there...

[#7]

looks like Avast was the problem  Uninstalled and loaded up avg and all seems well again, thanks for the help